Novel reversible and selective nerve agent simulant detection in conjunction with superoxide “turn-on” probing?

Analyst Pub Date: 2014-01-28 DOI: 10.1039/C3AN02267F

Abstract

Herein, we present fluorescein as a reversible fluorescent sensor for nerve agent simulants diethylchlorophosphate (DCP), diethyl methylphosphonate (DEMP), and diethyl cyanophosphonate (DECP). The superoxide allows for an “off–on” mechanism to regenerate fluorescein. The order of decrease in fluorescence intensity for nerve agent simulants is DCP > DEMP ? DECP.

Graphical abstract: Novel reversible and selective nerve agent simulant detection in conjunction with superoxide “turn-on” probing
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