Nazarov cyclization of dienylaziridines: synthesis of cyclopentadienyl/hydrinedienyl/indenyl glycines?
Organic & Biomolecular Chemistry Pub Date: 2015-07-15 DOI: 10.1039/C5OB01219H
Abstract
Cyclopentadienyl, hydrinedienyl, and indenyl glycines were synthesized using dienylaziridines as Nazarov cyclization precursors for the first time. Several substrates were synthesized to demonstrate the compatibility of this reaction. Asymmetric synthesis of these amino acids was also developed to show the additional scope of this method.
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Journal Name:Organic & Biomolecular Chemistry
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CAS no.: 89640-58-4