An efficient synthesis of quinolines via copper-catalyzed C–N cleavage?
Organic & Biomolecular Chemistry Pub Date: 2015-02-10 DOI: 10.1039/C5OB00075K
Abstract
An efficient method to synthesize substituted quinolines from ketones and 2-amino benzylamines is described. Copper-catalyzed C–N cleavage of amines followed by condensation with ketones deliver quinolines in moderate to high yields. The broad scope of substrates and the use of air as the sole oxidant make this transformation very attractive.
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Journal Name：Organic & Biomolecular Chemistry
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CAS no.: 89640-58-4
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