An effective route to β2-amino acid derivatives via Pd-catalyzed regioselective hydrocarboxylation of 1,2-disubstituted enimides?
Organic Chemistry Frontiers Pub Date: 2016-11-03 DOI: 10.1039/C6QO00353B
Abstract
An effective Pd(0)-catalyzed hydrocarboxylation of 1,2-disubstituted enimides with formic acid and HCOOPh is described. A variety of β2-amino acid derivatives are obtained in good yield with high regioselectivity without using external toxic CO gas.
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Journal Name:Organic Chemistry Frontiers
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CAS no.: 89640-58-4