An alternative one-pot gold-catalyzed approach to the assembly of 11H-indolo[3,2-c]quinolines?

Organic & Biomolecular Chemistry Pub Date: 2012-08-10 DOI: 10.1039/C2OB26380G

Abstract

A new one-pot approach was developed to construct the 11H-indolo[3,2-c]quinoline scaffold through a gold-catalysed reaction of 2-[(2-aminophenyl)ethynyl]phenylamine derivatives with aldehydes. The broad scope and the high regioselectivity of this new protocol as well as the mild and neutral reaction conditions make it a viable alternative to the previously reported procedures.

Graphical abstract: An alternative one-pot gold-catalyzed approach to the assembly of 11H-indolo[3,2-c]quinolines
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