Diphosphonites as highly efficient ligands for enantioselective rhodium-catalyzed hydrogenation

Chemical Communications Pub Date: 1900-01-01 DOI: 10.1039/A805524F

Abstract

Chiral ligands with achiral backbones such as ethano- or ferroceno-bridges linking two phosphonites derived from chiral diols such as binaphthol (BINOL) have been prepared; the corresponding Rh complexes are excellent catalysts in the hydrogenation of prochiral olefins such as itaconic acid dimethyl ester or 2-acetamido methyl acrylate, the ee values being 90–99.5%.

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