Cu-catalyzed β-functionalization of saturated ketones with indoles: a one-step synthesis of C3-substituted indoles?
RSC Advances Pub Date: 2016-09-13 DOI: 10.1039/C6RA19000F
Abstract
An effective one-pot synthesis of β-indolylketones from saturated ketones and indoles was developed. It is noteworthy that this methodology has a good functional group tolerance (alkyl, nitro, halogen, hydroxyl, methoxyl, carboxyl and ester) and is of great significance to the preparation of many indole heterocycles.
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Journal Name：RSC Advances
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CAS no.: 89640-58-4
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