Copper-catalyzed C–H acyloxylation of 2-phenylpyridine using oxygen as the oxidant?
RSC Advances Pub Date: 2018-05-03 DOI: 10.1039/C8RA01974F
Abstract
An efficient copper-catalyzed direct o-acyloxylation of 2-phenylpyridine with carboxylic acids using oxygen as the oxidant has been developed. Various acids including aromatic acids, cinnamic acids and aliphatic acids are effective acyloxylation reagents and provide the desired products in moderate to excellent yields. The reaction proceeds well under an oxygen atmosphere, making this method potentially practical.
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Journal Name:RSC Advances
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CAS no.: 89640-58-4