Umpolung of halide reactivity: efficient (diacetoxyiodo)benzene-mediated electrophilic α-halogenation of 1,3-dicarbonyl compounds?

Chemical Communications Pub Date: 2009-10-12 DOI: 10.1039/B915348A

Abstract

An efficient high-yielding (diacetoxyiodo)benzene-mediated α-halogenation of 1,3-dicarbonyl compounds utilising titanium tetrahalides as the halide source has been developed.

Graphical abstract: Umpolung of halide reactivity: efficient (diacetoxyiodo)benzene-mediated electrophilic α-halogenation of 1,3-dicarbonyl compounds
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