Alcohol-mediated direct dithioacetalization of alkynes with 2-chloro-1,3-dithiane for the synthesis of Markovnikov dithianes?
Organic & Biomolecular Chemistry Pub Date: 2017-04-19 DOI: 10.1039/C7OB00795G
Abstract
An alcohol-mediated dithioacetalization process that gains direct access to the corresponding Markovnikov-selective 1,3-dithianes using unactivated alkynes and nonthiolic/odorless 2-chloro-1,3-dithiane in a highly efficient manner has been developed. This methodology has the advantage of having mild reaction conditions, and the dithioacetalization process gives good to excellent yields with high Markovnikov-selectivity.
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Journal Name：Organic & Biomolecular Chemistry
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CAS no.: 89640-58-4
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