Visible-light induced decarboxylative C2-alkylation of benzothiazoles with carboxylic acids under metal-free conditions?
Organic & Biomolecular Chemistry Pub Date: 2018-11-30 DOI: 10.1039/C8OB02476F
Abstract
An effective protocol of photoredox catalyzed C2-alkylation of benzothiazoles with aliphatic carboxylic acids was disclosed. In the presence of an acridinium salt as a photocatalyst and air as an oxidant, a wide range of secondary or tertiary aliphatic carboxylic acids were employed as alkylation reagents, providing the desired products in good to excellent yields under mild reaction conditions with a broad substrate scope.
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Journal Name:Organic & Biomolecular Chemistry
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CAS no.: 89640-58-4