Total synthesis and absolute configuration reassignment of mollenines A and B?

Organic Chemistry Frontiers Pub Date: 2017-12-18 DOI: 10.1039/C7QO00985B

Abstract

The first total synthesis of the indole alkaloids mollenines A and B with the diketomorpholine skeleton has been accomplished in 9 and 10 steps with an overall yield of 11.4% and 9.3%, respectively. The absolute stereochemistry of the two natural products was corrected.

Graphical abstract: Total synthesis and absolute configuration reassignment of mollenines A and B
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