The p-toluenesulfonic acid catalyzed single pot synthesis of tetracyclic 1,2-dihydroquinolines: a metal free approach?
New Journal of Chemistry Pub Date: 2016-04-19 DOI: 10.1039/C6NJ00928J
Abstract
A simple, convenient and efficient p-toluenesulfonic acid catalyzed tandem reaction of aliphatic ketones with substituted anilines towards the synthesis of polysubstituted 1,2-dihydroquinolines has been developed. The ready availability of the catalyst, operational simplicity, cost effectiveness of the process and excellent regioselectivity mark some of the highlights of this methodology.
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Journal Name：New Journal of Chemistry
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CAS no.: 89640-58-4
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