A versatile synthesis of new pyrimidinyl nitronyl nitroxides?

Chemical Communications Pub Date: 2003-10-02 DOI: 10.1039/B309786B

Abstract

Pyrimidinyl nitronyl nitroxides where the bis-N-oxy fragment is included in a six-membered ring were prepared from diacetonamine by a sequence of reactions including a Grignard reaction, a Ritter reaction and oxidation of the intermediate pyrimidine; the properties of the 2-phenyl-substituted representative are fully described.

Graphical abstract: A versatile synthesis of new pyrimidinyl nitronyl nitroxides
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