The clerodane ring system: investigating the viability of a direct Diels–Alder approach?

Organic & Biomolecular Chemistry Pub Date: 2011-05-19 DOI: 10.1039/C1OB05422H

Abstract

A direct synthetic approach to the spiro-γ-lactone clerodane ring system has been investigated. This work builds on that of Jung and highlights the inherent difficulties associated with the otherwise obvious Diels–Alder approach.

Graphical abstract: The clerodane ring system: investigating the viability of a direct Diels–Alder approach
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