Synthesis of the first POSS cage–anthracycline conjugates via amide bonds?
New Journal of Chemistry Pub Date: 2016-05-11 DOI: 10.1039/C6NJ00347H
Abstract
Silsesquioxane derivatives widely used as polymer modifiers and catalytic supports have many interesting features making them potential nanocarriers in biomedicine. Two alternative synthetic routes were described, leading to the conjugates of functional POSS structures: octa(3-chloroammoniumpropyl)silsesquioxane and octa(carboxydecylthioethyl)silsesquioxane with anticancer drugs – anthracyclines.
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Journal Name：New Journal of Chemistry
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CAS no.: 89640-58-4
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