Total syntheses of natural products containing spirocarbocycles
Organic & Biomolecular Chemistry Pub Date: 2015-09-01 DOI: 10.1039/C5OB01524C
Abstract
The structures of natural products from a variety of sources contain spirocycles, two rings that share a common atom. The spiro motif is finding increasing inclusion in drug candidates, and as a structural component in several promising classes of chiral ligands used in asymmetric synthesis. Total syntheses of products containing all-carbon spirocycles feature several common methods of ring closure which we examine in this review.
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Journal Name：Organic & Biomolecular Chemistry
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CAS no.: 89640-58-4
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