Synthesis of artemisinin derived glycoconjugates inspired by click chemistry??
New Journal of Chemistry Pub Date: 2019-02-11 DOI: 10.1039/C8NJ05737K
Abstract
Herein we describe the synthesis of artemisinin based glycoconjugates (9a–i) through employing a Cu(I)-catalysed reaction between β-propargylated dihydroartemisinin (7a) and azido sugars (8a–i), with moderate to excellent yields. Our synthesized artemisinin based glycoconjugates (9a–i) could prove to be an interesting class of bioactive molecules, suitable for the study of their various biological activities.
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Journal Name:New Journal of Chemistry
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CAS no.: 89640-58-4