Synthesis of a class of binaphthyl monophosphine ligands with a naphthofuran skeleton and their applications in Suzuki–Miyaura coupling reactions?

New Journal of Chemistry Pub Date: 2018-03-13 DOI: 10.1039/C8NJ00412A

Abstract

A series of new monophosphine ligands containing a naphthofuran skeleton have been prepared, characterized and evaluated in palladium-catalyzed Suzuki–Miyaura coupling reactions. Using Pd2(dba)3L6 as the catalyst the reactions were performed with high catalytic activity under mild reaction conditions and the desired coupling products were obtained in good to excellent yields. The new catalyst system also showed broad substrate adaptability and practicality for gram-scale production.

Graphical abstract: Synthesis of a class of binaphthyl monophosphine ligands with a naphthofuran skeleton and their applications in Suzuki–Miyaura coupling reactions
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