Synthesis of pyrroloindolines and furoindolines via cascade dearomatization of indole derivatives with carbenium ion?
Chemical Communications Pub Date: 2015-02-13 DOI: 10.1039/C5CC00780A
Abstract
A highly efficient intermolecular cascade dearomatization of substituted indoles with benzodithiolylium tetrafluoroborate has been developed. This reaction provides a novel strategy to synthesise C3 methyl-substituted pyrroloindolines and furoindolines under mild reaction conditions, the utility of which has been demonstrated by the synthesis of esermethol and physovenine in a highly concise manner.
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Journal Name：Chemical Communications
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CAS no.: 89640-58-4
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