Simultaneous detection of single-nucleotide polymorphisms in a DNA bulge structure using a fluorine-modified bisbenzimide derivative?
Analyst Pub Date: 2015-12-08 DOI: 10.1039/C5AN02389K
Abstract
Using 3,5-bis(trifluoromethyl)benzene-modified bisbenzimide H33258, bulged-out nucleobases on a DNA strand can be detected by the chemical shift change in 19F NMR. Based on this technique, single-nucleotide polymorphisms on a DNA sequence can be analyzed simultaneously.
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Journal Name：Analyst
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CAS no.: 89640-58-4
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