Solid supported fluoronitroaryl triazenes as immobilized and convertible Sanger reagents – synthesis and SNAr reactions towards a novel preparation of 1-alkyl-5-nitro-1H-benzotriazoles?

Chemical Communications Pub Date: 2002-05-17 DOI: 10.1039/B201489K

Abstract

Synthesis of novel fluoronitroaryl triazenes in liquid phase and on solid support have been described; mild displacement of the fluoride ion with various nucleophiles provides access to substituted arenes which in turn can be cleaved to provide a unique access to 1-alkyl-5-nitro-1H-benzotriazole.

Graphical abstract: Solid supported fluoronitroaryl triazenes as immobilized and convertible Sanger reagents – synthesis and SNAr reactions towards a novel preparation of 1-alkyl-5-nitro-1H-benzotriazoles
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