Silver catalysed decarboxylative alkylation and acylation of pyrimidines in aqueous media
Organic & Biomolecular Chemistry Pub Date: 2015-01-06 DOI: 10.1039/C4OB02524E
Abstract
Decarboxylative alkylation or acylation reactions of simple pyrimidines have been developed in aqueous media. Using aliphatic carboxylic acids or 2-oxocarboxylic acids and pyrimidines as substrates and silver as the catalyst, the 4-substituted alkyl or acyl pyrimidines were isolated in moderate to good yields.
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Journal Name：Organic & Biomolecular Chemistry
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CAS no.: 89640-58-4
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