Alkali and alkaline earth metal ion binding by a foldamer capsule: selective recognition of magnesium hydrate?

Chemical Communications Pub Date: 2017-07-26 DOI: 10.1039/C7CC05422J

Abstract

Alkali and alkaline earth metal ion binding by an aromatic oligoamide foldamer was shown to induce its folding into a helical capsule. CD and NMR titrations revealed tight and selective binding of Mg2+. Crystallographic studies demonstrated that, depending on the metal, binding may involve the first or second coordination spheres of the metal hydrates.

Graphical abstract: Alkali and alkaline earth metal ion binding by a foldamer capsule: selective recognition of magnesium hydrate
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