A two-photon responsive naphthyl tagged p-hydroxyphenacyl based drug delivery system: uncaging of anti-cancer drug in the phototherapeutic window with real-time monitoring?
Chemical Communications Pub Date: 2020-07-20 DOI: 10.1039/D0CC01903H
Abstract
We report a two-photon responsive drug delivery system (DDS), namely, p-hydroxyphenacyl–naphthalene–chlorambucil (pHP–Naph–Cbl), having a two-photon absorption (TPA) cross-section of ≥20 GM in the phototherapeutic window (700 nm). Our DDS exhibited both AIE and ESIPT phenomena, which were utilized for the real-time monitoring of anti-cancer drug release.
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Journal Name:Chemical Communications
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CAS no.: 89640-58-4