The first total synthesis of gobichelin B: a mixed-ligand siderophore of Streptomyces sp. NRRL F-4415?
Organic & Biomolecular Chemistry Pub Date: 2018-03-13 DOI: 10.1039/C8OB00263K
Abstract
The first total synthesis of a structurally diverse mixed ligand siderophore, gobichelin B produced by Streptomyces sp. NRRL F-4415, is reported. The systematic assembly of the building blocks to synthesize Gob-B 1st half and Gob-B 2nd half and subsequent coupling of these two fragments followed by global deprotection using Pearlman's catalyst led to the isolation of gobichelin B in excellent yield and purity.
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Journal Name：Organic & Biomolecular Chemistry
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CAS no.: 89640-58-4
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