The first synthesis of both enantiomers of [α-2H]phenylacetic acid in high enantiomeric excess
Chemical Communications Pub Date: 2000-07-21 DOI: 10.1039/B003941L
Abstract
Arylmalonate decarboxylase (EC. 4. 1. 1. 76) catalysed decarboxylation followed by enantioface-differentiating protonation of [α-2H]- and [α-1H]phenylmalonic acid in 1H2O and 2H2O respectively, gave highly enantiomerically enriched (R)- and (S)-[α-2H]phenylacetic acid in quantitative yields.
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Journal Name：Chemical Communications
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CAS no.: 89640-58-4
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