Synthesis of analogues of linckoside B, a new neuritogenic steroid glycoside
New Journal of Chemistry Pub Date: 2013-08-14 DOI: 10.1039/C3NJ00514C
Abstract
A facile synthetic approach toward six designed analogues (2–7) of linckoside B, a new neuritogenic steroid glycoside isolated from the Okinawan starfish Linckia laevigata, has been developed. The key steroid aglycon was achieved by a dimethylaluminum chloride-mediated ‘ene’ reaction. A versatile strategy was employed for the construction of glycosidic bonds through Schmidt's procedure using a glycosyl trichloroacetimidate donor.
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Journal Name:New Journal of Chemistry
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CAS no.: 89640-58-4