Simple fluorescent probe derived from tetraphenylethylene and benzoquinone for instantaneous biothiol detection?

Analytical Methods Pub Date: 2012-08-16 DOI: 10.1039/C2AY25564B

Abstract

A novel probe incorporating tetraphenylethylene and benzoquinone into a molecule was synthesized and studied for the selective detection of biothiols. The probe was found to have a highly selective response to biothiols through a thiol–ene click-reaction with fluorescence turn-on feature. The observable color changes before and after biothiol addition indicated that the probe was suitable for naked-eye biothiol detection.

Graphical abstract: Simple fluorescent probe derived from tetraphenylethylene and benzoquinone for instantaneous biothiol detection
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