Simple and facile synthesis of tetralone-spiro-glutarimides and spiro-bisglutarimides from Baylis–Hillman acetates?

Organic & Biomolecular Chemistry Pub Date: 2008-02-06 DOI: 10.1039/B717843C

Abstract

A simple and convenient synthesis of di(E)-arylidene-tetralone-spiro-glutarimides from Baylis–Hillman acetates via an interesting biscyclization strategy involving facile C–C and C–N bond formation is described. Also, one-pot multistep transformation of the Baylis–Hillman acetates into di(E)-arylidene-spiro-bisglutarimides is presented.

Graphical abstract: Simple and facile synthesis of tetralone-spiro-glutarimides and spiro-bisglutarimides from Baylis–Hillman acetates
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