Self-assembling nanowires of an amphiphilic camptothecin prodrug derived from homologous derivative conjugation?
Chemical Communications Pub Date: 2016-11-11 DOI: 10.1039/C6CC07595A
Abstract
A novel amphiphilic camptothecin prodrug, CPT-ss-Ir, consisting of CPT, Ir and a disulfide bond linker, was synthesized, and it could self-assemble into nanowires in aqueous solution. Upon intracellular triggering, active CPT and Ir species were released to exert a considerable anticancer effect.
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Journal Name：Chemical Communications
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CAS no.: 89640-58-4
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