Synthesis of novel lidocaine-releasing poly(diol-co-citrate) elastomers by using deep eutectic solvents?

Chemical Communications Pub Date: 2011-11-22 DOI: 10.1039/C1CC15284J

Abstract

Poly(octanediol-co-citrate) elastomers containing high loading of lidocaine were synthesized at temperatures below 100 °C by means of using deep eutectic mixtures of 1,8-octanediol and lidocaine. The preservation of lidocaine integrity resulted in high-capacity drug-eluting elastomers.

Graphical abstract: Synthesis of novel lidocaine-releasing poly(diol-co-citrate) elastomers by using deep eutectic solvents
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