Quaternary ammonium salt as alkylation agent in three-component reactions for the synthesis of benzothiazoles in water?

RSC Advances Pub Date: 2014-06-04 DOI: 10.1039/C4RA04145C

Abstract

Substituted benzothiazoles are synthesized by metal-catalyst-free three-component reactions of o-iodoaniline, quaternary ammonium salt, and sulfur powder in water with moderate-to-excellent yields up to 95%.

Graphical abstract: Quaternary ammonium salt as alkylation agent in three-component reactions for the synthesis of benzothiazoles in water
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