Synthesis of a novel pseudodisaccharide glycoside as a potential glycosidase inhibitor
Chemical Communications Pub Date: 1900-01-01 DOI: 10.1039/A800279G
Abstract
An N-linked pseudodisaccharide 2 containing an inositol moiety in place of a glycopyranosyl residue has been synthesised to mimic the disaccharide unit, 3-O-(α-D-glucopyranosyl)-D-glucopyranose, cleaved by Glucosidase II during glycoprotein processing; an attempt to prepare the analogous 2-N-linked compound 1 as an inhibitor of Glucosidase I led to the novel N-phenyl derivative 10 of 2-amino-2-deoxy-D-glucopyranose.
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Journal Name：Chemical Communications
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CAS no.: 89640-58-4
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