Sonogashira cross-coupling under non-basic conditions. Flow chemistry as a new paradigm in reaction control?
Organic Chemistry Frontiers Pub Date: 2014-08-26 DOI: 10.1039/C4QO00198B
Abstract
The flow regime was implemented as a non-chemical alternative for the reaction control and detrimental acid byproduct sequestration in transition metal catalyzed cross-coupling reactions. The concept was illustrated on the Sonogashira reaction and resulted in a non-basic version of the cross-coupling protocols.
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Journal Name：Organic Chemistry Frontiers
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CAS no.: 89640-58-4
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