Photoinduced decarboxylative azidation of cyclic amino acids?

Organic & Biomolecular Chemistry Pub Date: 2018-12-26 DOI: 10.1039/C8OB02702A

Abstract

The direct decarboxylative azidation of cyclic α-amino acids has been achieved via visible light-mediated organo-photoredox catalysis. This synthetic strategy allows the simple preparation of azide-contaning building blocks and has been used in the selective modification of N-terminal proline residues of two di-peptides.

Graphical abstract: Photoinduced decarboxylative azidation of cyclic amino acids
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