Palladium-catalyzed synthesis of fluoreones from bis(2-bromophenyl)methanols?
Organic & Biomolecular Chemistry Pub Date: 2017-12-12 DOI: 10.1039/C7OB02895D
Abstract
A palladium-catalyzed synthesis method of fluorenones has been developed. A variety of bis(2-bromophenyl)methanols could undergo the reaction smoothly in the presence of Pd(OAc)2, affording a series of fluorenones in moderate to good yields (two steps). Mechanistic studies reveal that the reaction might be triggered by oxidation of alcohol followed by intramolecular reductive coupling.
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Journal Name：Organic & Biomolecular Chemistry
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CAS no.: 89640-58-4
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