Palladium-catalyzed direct C2-arylation of azoles with aromatic triazenes?
Organic & Biomolecular Chemistry Pub Date: 2019-10-02 DOI: 10.1039/C9OB01883B
Abstract
A highly efficient palladium-catalyzed arylation of azoles at the C2-position using 1-aryltriazenes as aryl reagents was developed. Azoles including oxazoles, thiazoles, imidazoles, 1,3,4-oxadiazoles, and oxazolines could react with 1-aryltriazenes smoothly to generate the corresponding products in good to excellent yields, and various substitution patterns were tolerated toward the reaction.
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Journal Name:Organic & Biomolecular Chemistry
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CAS no.: 89640-58-4