Organocatalytic enantioselective synthesis of β-amino sulfonic acid derivatives?
Chemical Communications Pub Date: 2021-07-21 DOI: 10.1039/D1CC03477D
Abstract
An unprecedented enantioselective conjugate addition reaction of sodium bisulfite to various nitrostyrenes occurred upon the influence of a bifunctional amino-thiourea organocatalyst; a strategy that opens a straightforward route to unprotected chiral taurine derivatives thanks to the reduction of the obtained β-nitroethanesulfonic acids into the corresponding amino derivatives.
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Journal Name:Chemical Communications
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CAS no.: 89640-58-4