Nickel-catalyzed C–P coupling of aryl mesylates and tosylates with H(O)PR1R2?

Organic & Biomolecular Chemistry Pub Date: 2012-02-21 DOI: 10.1039/C2OB25225B

Abstract

A method was developed for the nickel-catalyzed phosphonylation of aryl mesylates and tosylates with H(O)PR1R2. To the best of our knowledge, this is the first example of nickel-catalyzed C–P coupling of aryl mesylates and tosylates. Most of the substrates gave moderate to good yields under our catalytic system.

Graphical abstract: Nickel-catalyzed C–P coupling of aryl mesylates and tosylates with H(O)PR1R2
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