Oscillatory three-phase flow reactor for studies of bi-phasic catalytic reactions?

Chemical Communications Pub Date: 2015-04-16 DOI: 10.1039/C5CC02051D

Abstract

A multi-phase flow strategy, based on oscillatory motion of a bi-phasic slug within a fluorinated ethylene propylene (FEP) tubular reactor, under inert atmosphere, is designed and developed to address mixing and mass transfer limitations associated with continuous slug flow chemistry platforms for studies of bi-phasic catalytic reactions. The technique is exemplified with C–C and C–N Pd catalyzed coupling reactions.

Graphical abstract: Oscillatory three-phase flow reactor for studies of bi-phasic catalytic reactions
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