Nickel catalyzed α-arylation of ketones with aryltrimethylammonium triflates?
Organic & Biomolecular Chemistry Pub Date: 2016-07-18 DOI: 10.1039/C6OB01299J
Abstract
Nickel-catalyzed α-arylation of ketones involving aromatic C–N cleavage has been accomplished. Intermolecular coupling of aromatic ketones with a variety of aryltrimethylammonium triflates was achieved in the presence of Ni(COD)2, IPr·HCl, and LiOBut, giving α-arylated ketones in reasonable to excellent yields.
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Journal Name：Organic & Biomolecular Chemistry
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CAS no.: 89640-58-4
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