Oxidative cross coupling reaction mediated by I2/H2O2: a novel approach for the construction of fused thiazole containing coumarin derivatives?
RSC Advances Pub Date: 2015-11-24 DOI: 10.1039/C5RA20405D
Abstract
Various 2-phenyl-4H-chromeno(3,4-d)thiazol-4-one derivatives have been synthesized through C–H bond activation using sodium sulfide as a source of sulfur atoms and by employing I2 as a catalyst and H2O2 as the terminal oxidant. Transition metal-free oxidative coupling for the formation of C–S bonds is one of the salient features of the present protocol. A number of thiazole containing coumarin derivatives having various substituents has been accomplished in good yields.
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Journal Name:RSC Advances
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CAS no.: 89640-58-4