Nickel-catalyzed methylation of aryl halides/tosylates with methyl tosylate?

Chemical Communications Pub Date: 2017-08-23 DOI: 10.1039/C7CC06106D

Abstract

This work describes the cross-electrophile methylation of aryl bromides and aryl tosylates with methyl tosylate. The mild reaction conditions allow effective methylation of a wide set of heteroaryl electrophiles and dimethylation of dibromoarenes.

Graphical abstract: Nickel-catalyzed methylation of aryl halides/tosylates with methyl tosylate
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