One-step synthesis of novel glycosyltransferase inhibitors?

Chemical Communications Pub Date: 2012-11-05 DOI: 10.1039/C2CC36798J

Abstract

A one-step synthesis of two 5-CF3 UDP-sugars is reported. These non-natural sugar-nucleotides are micromolar inhibitors of two different galactosyltransferases.

Graphical abstract: One-step synthesis of novel glycosyltransferase inhibitors
Recommended Literature