Nickel-catalyzed regioselective arylation of aromatic amides with aryl iodides enabled by an N,O-bidentate directing group?
Organic & Biomolecular Chemistry Pub Date: 2018-10-30 DOI: 10.1039/C8OB02237B
Abstract
A bidentate directing group enabled regioselective arylation of C(sp2)–H bonds in aromatic carboxamides with aryl iodides under nickel-catalysis is reported, which provides the corresponding products in moderate to good yields. This protocol using the inexpensive and low-toxic Ni catalyst can tolerate a wide range of functional groups.
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Journal Name:Organic & Biomolecular Chemistry
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CAS no.: 89640-58-4