Oxidative polymerization of catecholamines: structural access by high-resolution mass spectrometry?

Polymer Chemistry Pub Date: 2017-04-26 DOI: 10.1039/C7PY00506G

Abstract

We introduce the high-resolution electrospray ionization mass spectrometric (ESI MS) structural elucidation of polymerized 3,4-dihydroxy-L-phenylalanine (L-DOPA) carrying 1-methoxy-2,2,6,6-tetramethylpiperidin-4-amide groups in the side chain. Critically, our powerful ESI MS platform unambiguously revealed the structurally diverse character of this multifunctional bio-adhesive polymer system.

Graphical abstract: Oxidative polymerization of catecholamines: structural access by high-resolution mass spectrometry
Recommended Literature