Novel soraphens from precursor directed biosynthesis?

Chemical Communications Pub Date: 2003-05-09 DOI: 10.1039/B303543N

Abstract

Six novel halogenated soraphen analogues have been isolated from the wild-type producing organism using precursor directed biosyntheses; the best ‘delivery vehicle’ for the novel starter acids was cinnamate but ortho substituents were not tolerated by the soraphen PKS.

Graphical abstract: Novel soraphens from precursor directed biosynthesis
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