A novel one-pot method for the synthesis of substituted furopyridines: iodine-mediated oxidation of enaminones by tandem metal-free cyclization?
Chemical Communications Pub Date: 2014-12-08 DOI: 10.1039/C4CC08834D
Abstract
A novel iodine-mediated oxidative tandem cyclization reaction of simple enaminones has been developed for the synthesis of substituted furopyridines through C–C/C–N/C–O bond formation in a one-pot procedure. Substituted furopyridines are obtained in moderate to good yield. In addition, I- and Br-substituted furopyridines have been successfully produced by the electrophilic substitution of N-iodo- or N-bromosuccinimide.
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Journal Name：Chemical Communications
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CAS no.: 89640-58-4
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