Ligand-free palladium-catalyzed facile construction of tetra cyclic dibenzo[b,h][1,6]naphthyridine derivatives: domino sequence of intramolecular C–H bond arylation and oxidation reactions?
RSC Advances Pub Date: 2016-03-04 DOI: 10.1039/C6RA00505E
Abstract
A ligand-free Pd-catalyzed approach has been developed for the synthesis of dibenzo-fused naphthyridines. The reaction involves a one-pot domino sequence of reactions involving C–H functionalisation and oxidation. The reaction was applicable to a wide range of substrates, giving the required product. Further fluorescence studies were performed where the Stoke's shift was found to be dependent on the polarity of the solvent.
![Graphical abstract: Ligand-free palladium-catalyzed facile construction of tetra cyclic dibenzo[b,h][1,6]naphthyridine derivatives: domino sequence of intramolecular C–H bond arylation and oxidation reactions](http://scimg.chem960.com/usr/1/C6RA00505E.jpg)
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Journal Name：RSC Advances
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